Dan Ostermayer

Dan Ostermayer 's avatar
Dan Ostermayer
npub1gc64...uyek
physician metabolic health maximalist 📚 co-sleeping https://a.co/d/0itAvPV the simple world https://a.co/d/5u4BdMU 📚
the only thing that can be tested in a randomized double blind placebo controlled trial is a pharmaceutical intervention. everything else, even if randomized gets labeled as lesser quality evidence. (can't test organ meat ingestion and exercise this way) this is why evidence based medicine has been co-opted by drug based interventions. those molecules get the highest stamp of evidence based guidelines
the only thing that can be tested in a randomized double placebo controlled blind trial is a pharmaceutical intervention. everything else, even if randomized gets labeled as lesser quality evidence. (can't test organ meat ingestion and exercise this way) this is why evidence based medicine has been co-opted by drug based interventions. those molecules get the highest stamp of evidence based guidelines
file this under the obvious for must of here but a shocker for the mainstream. high saturated fat creates the cholesterol building blocks for a healthy brain "Consumption of ≥50 g/d of high-fat cheese (>20% fat) was associated with a reduced risk of all-cause dementia (HR 0.87; 95% CI, 0.78–0.97) and VaD (HR 0.71, 95% CI 0.52–0.96) compared with lower intake (<15 g/d). An inverse association between high-fat cheese and AD was found among APOE ε4 noncarriers (HR 0.87, 95% CI 0.76–0.99, p-interaction = 0.014). Compared with no consumption, individuals consuming ≥20 g/d of high-fat cream (>30% fat) had a 16% lower risk of all-cause dementia (HR 0.84, 95% CI 0.72–0.98). High-fat cream consumption was inversely associated with the risk of AD and VaD. " https://www.neurology.org/doi/10.1212/WNL.0000000000214343