Should a 20-year old consume deuterium-depleted water? How about a 53-year old? Nathan Walz: "Lynn wants to know if she should give her 20 year old son deuterium-depleted water, or would somebody his age need deuterium for growth and development?" Dr. Jack Kruse: "Yeah, I'm gonna tell you that I think that deuterium-depleted water for the first couple of decades, unless somebody has a significant mitochondrial disease, it's not needed. Deuterium-depleted water is best when heteroplasmy rate is higher. I wouldn't assume a 20-year old would have that, unless the kid was born would say a childhood cancer, or an autoimmune condition, or some kind of tumor. That would be the only time I would do that. "It's a good thing to do; don't get me wrong. I still think it's not a bad way to go. But the deuterium-depleted water pathway is a backup pathway. You're designed to make it mostly in your mitochondria. But you can offset a bad mitochondrial matrix by utilizing the oxidative branch of the pentose phosphate pathway. That's actually how drinking water can affect that. It also then has a spillover effect to another pathway, and that's called the NADPH pool. That pool is designed to really take care of RNA and DNA. And usually in young people that's not a big deal. There's another backup pathway that I've written about on my Patreon blogs. […] It's called the serine glycine inner conversion, and the way to use that is to use animal fats or plant fats to access that, and that's another way for you to help fix your matrix. "But again, that's also something I don't think a 20-year old really needs to do. Really, the key stuff somebody's 20 needs to do is the stuff that we talked about on the regular on the regular site, like the leptin prescription, cold thermogenesis, eating a seasonal diet, trying to mind your EMFs, definitely blocking blue light at night. Because if you don't do those things that's actually what allows the deuterium to go into your matrix, and then that leads to heteroplasmy or diseases, so that when you are me and Rich's age, you got to worry about it. "I'm 53, Rich is 65. For us, deuterium-depleted water is a good thing. Why? Because I'm in my sixth decade, Rich is in his seventh, and we know from Doug Wallace's work that every decade we live our heteroplasmy by chance alone goes up 10%. So him and I are closer to our ends so we need to do more, and that's why him going to the cenotes, and me down here drinking a lot of deuterium-depleted water from the cenotes, that's part of the reason I come here so many times. This year alone, this is my eighth time in 2017, and I'm here for a whole week and I'll be here for another week. This place is, when you said, 'Is it the Fountain of Youth?' You say it in a joking fashion, but to be quite honest with you, when you have a high heteroplasmy rate, this place is the shit. That's all I can tell you." Dr. Jack Kruse with Nathan Walz @ 23:44–26:56 (posted 2018-01-08)