Your quads, glutes and hips are the first to weaken with age. Three simple exercises to help you live independently "The muscles that help you stand up, your quadriceps, glutes and hips, are the first to weaken with age. They're also the ones that determine whether you can live independently. The stronger they stay, the longer you stay free. […] "Today, I'll walk you through three simple, science-backed exercises that thousands of Americans over 60 are using to rebuild their legs, improve circulation, and regain balance right from their living room. These are not workouts. They're signals your body understands. Let's bring that strength back, one small step at a time. […] "This first exercise […] looks small, but it flips the switch that wakes your circulation. […] Sit in a sturdy chair, feet flat on the floor, back straight, shoulders relaxed. Now, lift your toes towards you, hold one heartbeat, then press them down, and lift your heels. Feel that rhythm: Heel toe, heel toe, like a slow wave rolling through your ankles. Keep breathing. 10 to 20 reps per set, up to three sets a day. […] "The next challenge is teaching those newly revived muscles how to stabilize your entire body when you stand, […] the exercise that turns trembling legs into steady pillars again. […] "Stand behind a sturdy chair or at your kitchen counter. Hold on lightly, just enough for balance, and place your feet shoulder width apart. Now slowly rise onto your toes. Pause at the top. Feel the stretch along your calves, and then lower yourself back down with control. No bouncing, no rushing, just steady, deliberate movement. 10 repetitions, rest for a minute, then repeat. Work your way up to three sets of 20 over time. […] "If the ankle pumps wake your circulation, and the calf raises restore balance, this final movement rebuilds your raw power, the ability to rise, to climb, and move through the world on your own terms. […] "Take a sturdy chair, one that doesn't roll, and place one or two firm pillows on the seat. Sit down slowly, feet flat, knees in line with your toes, hands resting lightly on your thighs. Now press your feet into the floor, tighten your core, and rise until you're fully standing. Pause. Feel your legs engage. Then lower yourself back down until you just touch the pillow. That gentle tap keeps your muscles under control rather than letting gravity take over. Start with one set of five. Rest. Then build to three sets of 10 as your endurance grows. Don't rush the process. The slower you move, the more your muscles learn precision. And precision builds true strength." HealThrive Talk @ 08:39–08:48, 00:38–01:57, 04:02–05:14 & 08:19–09:34 (posted 2025-11-08)

How to avoid glyphosate. Eat certified organic whole foods, organic eggs, animal fats, butter, sour cream, full-fat milk, half and half. Avoid processed foods. Humic acid and fulvic acid helpful in removing glyphosate from the gut Aastha Jain Simes: "If someone wants to avoid glyphosate as much as possible, what are some practical suggestions you would give them?" Dr. Stephanie Seneff: "Absolutely go on certified organic diet. Only buy certified organic foods, and I would recommend only buying whole foods; don't eat processed foods. Anything that has a whole bunch of ingredients don't buy it, you know, one of the soy protein bar, even organic soy protein bar, I wouldn't buy it. So you want eat high nutrient density foods as well, for example, organic eggs. That's a terrific food because they got so many vitamins and minerals as well as of course sulfur. "And healthy fats. I really recommend animal fats, and I love butter and sour cream. Those are nice low-deuterium fats. Actually interesting, because milk has low-deuterium, and that's intentional, I think, because the infant needs to have low deuterium in its diet. […] I only drink full-fat milk. In fact, if I have cereal I put half and half on it, so even more fat than full-fat milk. […] And by the way, butter has very low deuterium, so natural organic butter is a terrific food. […] So the high fat diet is low deuterium. […] "I mentioned the humic acid and fulvic acid. People are find that that's helpful for removing glyphosate from the gut. And probiotics, I really think if you eat a lot of probiotic foods, it's good anyway, because they can help with your gut microbes. They could have bacteria that could metabolize glyphosate in them. I don't know whether that's true or not, but I would hope that could be." Dr. Stephanie Seneff with Aastha Jain Simes @ 01:13:35–01:14:43 (posted 2024-05-30)

Glyphosate substitutes for glycine, thereby damaging collagen. Glyphosate may contribute to pelvic prolapse, joint pain, neck pain, back pain Dr. Stephanie Seneff: "[…] I called it a glyphosate susceptibility motif that certain proteins have. […] If that glycine is mutated to something else that protein is dead in the water, and there were many proteins that had tremendous sensitivity to substitutions. If glycine is substituted by a different amino acid in the code, that protein is broken. […] Glyphosate is pretending to be glycine. […] When the machinery sees the code for glycine, it grabs glyphosate instead because it fits perfectly. […] That can really mess things up, because the glyphosate has this extra bulky thing that's stuck out into the space. In particular, when they bind phosphate, glyphosate's methylphosphonate unit fits into the place where phosphate from the substrate is supposed to go. So the substrate can't fit anymore and the protein can't do its job." […] Aastha Jain Simes: "What are some of the first order effects of what happens in the body?" Dr. Stephanie Seneff: "Yes. There's so many. Collagen is a good example, because collagen is the most common protein in the body. A third of our proteins are collagen molecules. It forms the glue. It basically is in the connective tissue, in the bones, in the joints, even in the brain. It's very common in our body. And collagen has long swaths of G-X-Y, G-X-Y, G-X-Y, G-X-Y, every third amino acid is a glycine, tremendous opportunity for glyphosate to do mischief. I definitely think that glyphosate messing up collagen is causing a lot of diseases of the bones and joints and even of the gut. "There's a problem with sagging, […] pelvic prolapse, […] where the organs are sort of collapsing down into the bottom of the body, because they can't hold themselves up, because the collagen is so weak and flabby that it can't actually work. This is a kind of condition that's happening, and it can be a pretty serious problem. I think it's because the collagen's not forming correctly, and then […] the connective tissue is not strong anymore; it's too weak. "I think that's causing a lot of problems also in the bones and the joints. People have a lot of issues with joint pain. We have a lot of replacement, hip replacement therapy, and knee joint, you know, knees are giving out. You look at Americans over the age of maybe 60, they're pretty much hobbling around. Many of them have to use a walker or a cane. […] And of course back pain is a huge problem. There's a lot of pain associated with these things: neck pain, back pain. People get on opioid drugs, so now we have an opioid drug crisis. I think glyphosate may be contributing to all of that, because messing up collagen could explain all of that." Dr. Stephanie Seneff with Aastha Jain Simes @ 16:08–17:35 & 19:39–21:50 (posted 2024-05-30)

A high fat diet is the most deuterium-depleted diet. When treating cancer with deuterium-depleted water, avoid taking high dose antioxidants, avoid intense exercise, avoid sauna or hot baths Dr. Max Gulhane: "The question about diet in terms of deuterium. Essentially it's sounds like a high fat, carnivore diet is the most deuterium-depleted diet. Is that correct?" Dr. Gábor Somlyai: "Yeah, I agree. Yeah, sure. So we recommend people when starting to drink DDW at the same time change the diet, some kind of ketogenic-type diet. I never say be strict ketogenic because they cannot keep it on a long term. They should find the best way when they can optimize it and keep it on a long period of time." Dr. Max Gulhane: "Yeah, and Dr. Boros, who I talked to earlier, was talking about the benefit of high fat carnivore for all the reasons of promoting metabolic water function and optimizing mitochondrial function. So to me it sounds like a high fat diet, ketogenic or carnivore-type diet, would be the most optimal to do in addition to drinking the deuterium-depleted water for cancer or for metabolic disease." Dr. Gábor Somlyai: "Yeah. I fully agree. Yes." Dr. Max Gulhane: "Yeah. OK, and again, I think I just want to make the point for my listeners, is that there's no reason why we can't do this therapy in addition to other things, like exercise, like respecting our circadian rhythm and our light environment. It's great that this is simply just another tool in the toolbox. That's how I kind of understand it to be." Dr. Gábor Somlyai: "There are a couple of thing what we do recommend not to do, and this is very important. So for example, I sometimes I didn't understand why the people do not show any improvement even consuming DDW. And later it's turned out those who are taking antioxidants on a high dose, that prevent the efficacy of DDW, and this is the reason of the radicals. So when we are going to trigger radicals, hopefully triggering the necrosis, but if they're taking vitamin C, E, A, selenium, that way we help the cancer cells to work against DDW. This is what we recommend. "The other we do not recommend the exercises and loading test, because then the lactic acid increasing in the blood, no enough oxygen, and all these thing I again found that those cancer patients they were fine starting to doing exercise, they relapse. "And the third is no sauna, no hot bath, because again the higher body temperature modify the metabolism, which again somehow help the cancer cells to treat the challenges of the DDW. "So drinking DDW and not doing that three different thing to optimize the efficacy of DDW." Dr. Max Gulhane: "OK, thank you for making those points. […] Obviously walking is OK. But you're suggesting that high intensity or long distance running is a bad idea." Dr. Gábor Somlyai: "Yeah." Dr. Gábor Somlyai with npub19yjldzc98lsesatjncxzgunm8xpdjsr5tva3sjc9ggyqsjh5hedst2unad @ 01:02:13–01:05:55 (posted 2024-02-24)

"If you don't see the sunrise you cannot properly utilize the TCA cycle. In other words, you can't burn fat, can't use beta oxidation." — Dr. Jack Kruse with Jonathan Jarecki @ 54:53–55:00 (posted 2024-12-23)

Humans' biggest risk is their own Dunning-Kruger effect Dr. Jack Kruse: "At the end of every year, from about I guess it's September 30th to December 15th, I have a notebook, and I write all the things down I currently believe, and then I challenged them. Is there any new data out there that causes me to fix this? "Why do I do that? Because I understand that humans' biggest risk is their own Dunning-Kruger effect. "I came up with this idea 25 years ago when I left residency. I started to think about in real life, we don't have any process like M&M conference, which is morbidity and mortality. I said, 'So how do you stay up to date?' […] I said, '[…] I think the best thing is I need to do this myself. I need to have my own M&M conference.' And that's where I came up with the idea." Dr. Jack Kruse with Jonathan Jarecki @ 35:12–36:08 (posted 2024-12-23)

Steps taken by Sarah Kleiner to get pregnant at age 43. Dr. Kruse's advice Dr. László Boros: "Can I ask a quick question, because you told me in your email that you are 23 weeks?" Sarah Kleiner: "27. 27 weeks now." Dr. László Boros: "Congratulations." Sarah Kleiner: "Thank you. Yeah." Dr. László Boros: "Was your husband also on deuterium-depleting protocols or it was only you?" Sarah Kleiner: "Just me. Just me. We had yeah, I just turned 43. We had decided we're going to try for the baby, and we had been trying for a couple of years and just not successful. And so I changed my whole lifestyle, too. I didn't just drink the water. I mean, that's when I got very interested in circadian rhythms. Anytime I could be in the woods, I was in the woods. I started cold plunging in ice water, 30 degree ice water [laughs], going out on my deck in a bathing suit in the winter and ice plunging. Red light therapy. Just everything I could. And then a ketogenic diet, you know, very high fat, bone marrow, as healthy as I could. "And I did do [deuterium-depleted] water from September to December. And then one of my friends that we're all kind of connected with Dr. Kruse and a lot of his teachings, he said, 'Well, if you're going to try for the baby then stop the water, and stop the cold plunging in January.' And so I stopped it in January and then that was the month that it worked. "And so that's what, you know, during all this time is when I was just super interested in the whole concept of deuterium, because there's so many women that are struggling to get pregnant, not just my age you know. Yeah, I'm older to try to get pregnant, but there's women in their 30s and in their 20s. And when I was exploring different fertility clinics, they're all booked up six months in advance. And then you go and it's full of younger women, too. So it's a major problem right now. Dr. László Boros: "Yeah, because if you think about it, sperm is propelling itself, the sperm cells using these nanomotors. They swim in a liquid where viscosity is very critical to reach the egg, the oocyte that was released from a mature follicle. And all these factors eventually add up, and would help fertilization by deuterium depletion. I would most desirable on both sides, but obviously it would make a big difference even just if you follow a certain lifestyle." Dr. László Boros with Sarah Kleiner @ 34:46–37:34 (posted 2022-08-10)

Chemically made supplements of methionine, melatonin, NAC, choline are not low deuterium. As such, they are harmful. Most of these supplements are chemically made. Biologically made methionine, NAC, melatonin, choline are low in deuterium Tristan Scott: "That's so fascinating in terms of the synthetic. I hate when a lot of these, maybe it's more the Fitness Bros, or the 'Show me the study' guys are like, 'Well, there's no difference between synthetic [methionine] and natural components.'" Dr. Stephanie Seneff: "That is not true." Tristan Scott: "Now it's like, 'Well, we have here some proof that actually there is.' Why is there actually a difference? Is it just because they don't consider those deuterium-depletion steps that our innate biology has built in?" Dr. Stephanie Seneff: "Precisely, yeah. First of all I want to say that melatonin has the same problem. And N-acetylcysteine does, too. So the acetyl in N-acetylcysteine, that's going to be low deuterium if it comes from the gut microbes, but if it's made synthetically it won't. So if you're taking a supplement N-acetylcysteine, no guarantee that that acetyl is going to be low deuterium. "And melatonin, melatonin has both an acetyl and a methyl attached to it. It starts out as tryptophan, which of course comes out of the shikimate pathway. Tryptophan gets turned into serotonin, which is another neurotransmitter. And then serotonin gets turned into melatonin, and when you do that you add a methyl and an acetyl. Both of them are going to be low deuterium if they came from a biological source. "But if you eat a methionine that's made in the chemistry lab, which it typically is, that's how you can do it cheaply. […] Imagine growing microbes and having to purify the methionine that's in there with all the other stuff that's there, right? Or the melatonin. That's a lot of work. So you'd rather just make it chemically. You can get a pure supply more easily if you don't have to deal with all the biological life that might be mixed up in there and cause problems. So most of these supplements are chemically made, and they're not going to be good, so I don't recommend any of these supplements that are going to have these. "Choline is another one. Choline is going to be low deuterium if it comes from a biological source. But if they're making in the chemistry lab, forget it. It's not good for you. So I think people are loading up on supplements that are actually hurting them because they're not supplying the low deuterium resource that would have happened if it had been biological. "Now I need to explain why that's the case, because it's super fascinating. I figured it out based on a paper that was written in the 1960s. […] That paper showed […] that the gas that was made by these [gut] microbes, hydrogen gas, H₂, had 80% of the deuterium gone. It was down by a factor of five. 80% gone. So that becomes a really good source of low deuterium hydrogen. And then the microbes are very careful to make sure […]" Dr. Stephanie Seneff with npub1yd2h2lrwchshvm46jq7auh65tjkxmgnapkavh7tjtqq07kknupxsa980tv @ 58:17–01:01:20 (posted 2023-12-05)

If you don't wear sunglasses, you don't burn. You're triggering the POMC production in your brain and your skin to make new melanin. Throw out your sunglasses! There's nothing more powerful than melanin; you want more of that Dr. Francisco Gutierrez: "And then the other thing that really caught my attention was the use of sunglasses. I threw them away." Dr. Alexis Cowan: "Great." Dr. Francisco Gutierrez: "And you know, it's crazy. Ever since I've heard you say this in podcast that you've also had the same experience that I'm gonna share, is that after you don't wear sunglasses, you don't burn. Like I can literally be here UV 13. I've been there like two, three, four hours, no burn, zero." Dr. Alexis Cowan: "Yes. It's wild. And it also makes perfect sense too, because then you're triggering the POMC production in the brain and the skin and you're getting basically double the dose of the MSHs that are needed for making new melanin. "Every time I go out in public, it's just crazy the number of people I see wearing sunglasses and AirPods. Like so many people wearing sunglasses and AirPods at the same time. I just want to make a T-shirt that says like, 'Throw out your AirPods and sunglasses!' because this is ridiculous. "And with regards to cycling, I'm big into cycling, too. But I noticed like I go out and I like basically wear like short shorts and like a sports bra and like I'm not wearing glasses or anything. And then I see other cyclists and they're covered with the thin clothes from head to toe, sunglasses, helmet. It's like nothing is showing." Dr. Francisco Gutierrez: "I know. It's crazy. The cycling group that I that I go out cycling, a lot of them are from the Dominican Republic, so their skin is dark. Yet they slather themselves with sunblock and put sunglasses on. In the 44th north latitude." Dr. Alexis Cowan: "Oh, no. That's awful. Yeah that reminds me, there's a brand of sunscreen, I wanted to like burn something down when I read this, but there's a brand of sunscreen called Black Girl Sunscreen [laughs]. And I'm like, 'Oh my gosh.' There's a lot of programming in Western culture around, and also in other cultures too. Even in the East, you're frowned upon for having darker skin, like it's bad. Everybody's trying to have lighter skin because it's supposed to be more aesthetic. But when you learn about the biology of melanin, it's like there's nothing more powerful than that. You want more of that." Dr. Francisco Gutierrez: "You want more of that. Yeah, absolutely. No, I agree." Dr. Francisco Gutierrez with Dr. Alexis Cowan @ 37:53–40:12 (posted 2025-05-23)

Glyphosate damages gut microbiota, raises gut pH, damages acid-loving microbes' ability to make butyrate. The colonocytes lining the gut get sick from a lack of butyrate, which leads to IBD and eventually colon cancer Tristan Scott: "Yeah, I think it's incredible, and that's one of the main mechanisms or areas that people are pretty familiar with is that [glyphosate] is like a nuke for your gut, really. But when you get into how it works and then how something I realized is just how important the gut is for producing things like B vitamins. I think you said in your book that it augments the the dietary intake of it. So that's something that especially folks in the diet community pretty much never talk about, and that care we need to have for our microbiota and just how the diversity has been just decreasing tremendously over decades. If you look at like studies comparing the Hadza in Africa and Tanzania compared to the modern man, it's so crazy." Dr. Stephanie Seneff: "I think I talk about that in my book. I have a chapter on the gut which I've spent a long time on it. The gut is a hard problem when you start looking. The research literature has blossomed. There's tons of papers now, and they're very complex with all these pretty colors, and all these Venn diagrams, and all these different microbes in different amounts, and it's extremely overwhelming. But I eventually dug a story out of that I feel that I'm quite confident about which is super interesting. "Glyphosate causes the pH of the gut to go up, and I think that's because of these undigested peptides. Normally the proteins come in, they get broken down into the amino acids, they get absorbed in the midgut, they get absorbed into the system, and now everybody's happy, because you need those amino acids to make human proteins. "But they don't get digested. They end up in the lower gut still as peptide sequences. And then there's gut microbes there that can break them down, but break them down all the way, because you can no longer absorb those amino acids. They have to be broken down all the way to nitrogen, which is going to be ammonia, which is going to be a high pH. So you raise the pH of the gut, and then that causes the acid-loving microbes to get sick they can't really live in this high pH. Those are the ones that make the acetate, the butyrate, the propionate. These are short-chain fatty acids that are incredibly important for the host, because the colonocytes lining the gut, their main food is butyrate, and butyrate comes from these acid-loving bacteria. And so when they can't make the butyrate, the colonocytes get sick, and then you end up with inflammatory bowel disease and irritable bowel disease, and eventually you get you know colon cancer and things like that, all of which are going up dramatically in step with the rising glyphosate usage in this country." Dr. Stephanie Seneff with npub1yd2h2lrwchshvm46jq7auh65tjkxmgnapkavh7tjtqq07kknupxsa980tv @ 26:21–28:49 (posted 2023-12-05)