In UK, summer blood pressure is significantly lower than winter, as great an effect as a drug. If you're a male living in Scotland, you are 30% more likely to drop dead in a week in January than a week in August. Vitamin D supplementation has no effect on myocardial infarctions, no effect on strokes, and no effect on cancer deaths
Professor Richard Weller: "When you analyze blood pressure by the month of the year in which the blood pressure was taken, we see there's a huge seasonal variation in blood pressure in the UK. So in summer blood pressure is significantly lower than winter. And in fact the effect of season is as great as the effect of a drug in lowering blood pressure. So what this might suggest to you is that sunnier countries, or within a country, sunnier times of the year correlate with lower blood pressure. [β¦] The more UV that falls the lower cardiovascular disease incidence, which is a sequela of high blood pressure. So that's observational data.
"The next bit of observational data is really looking at vitamin D. So UVB formation is responsible for vitamin D synthesis in man. So blood vitamin D levels are a great indicator, a biomarker for how much sunlight and specifically UVB you've had. And we know that people with lower measured vitamin D levels are more likely to have hypertension, more likely to have cardiovascular disease, more likely to die of stroke, and in fact more likely to die of any cause whatsoever. So that's observational data.
"The problem is when you carry out interventional studies, when you enter people into randomized placebo controls, double-blinded trials of vitamin D supplementation, it does pretty much nothing. So this is a meta-analysis, a combined analysis of multiple trials of vitamin D supplementation published in the Lancet, gosh, 12 years ago now. Giving people vitamin D has no effect on myocardial infarctions, no effect on strokes, and no effect on cancer deaths. And the biggest study of all was completed about five or six years ago in America. So this was is a study called the VITAL Study funded by the NIH in America. 25,000 Americans randomized, half to get vitamin D supplements for five years, half to get placebo. The results have been published largely in the New England Journal, and the results are broadly negative, negative, negative, negative. Some possible effects on autoimmune disease. So that was 25,000 people for five years. The Australians ran a smaller study, 21,000 people for five years. Half get vitamin D, half get placebo. Results are negative, negative, negative, negative. So, it's not the vitamin D.
"And this is an editorial from the New England Journal from 2022, four years ago now, saying, 'Adding those findings to previous reports, etc., etc., people should stop taking vitamin D supplements to prevent major diseases or extend life.' So clinical trials confirm it's not the vitamin D. So vitamin D is a biomarker of a sunlight exposure and it prevents rickets in children. You know it has some benefits, prevention of rickets being the main one. [β¦]
"If you're a male living in Scotland, you are 30% more likely to drop dead in a week in January than a week in August. Huge, huge. We've just passed the equinox, heading the wrong way. Time of year when I start to get a bit antsy. You know, summer's fine. Am I going to survive another winter? You know, the data is pretty serious. We know that vitamin D accounts prevention of rickets, but what about the rest? And that's really the question that we're facing now. So this is observational data and the vitamin D debunked by trial data: limited benefits."
Professor Richard Weller @ 10:50β15:12 (posted 2025-10-11)
"I regard consciousness as most fundamental." β Max Planck. Consciousness, energy and matter. _The Case Against Reality_
Martin Picard, PhD: "Max Planck, who is a quantum physicist, at the end of his career he wrote at length about this and he ended up saying, 'I regard consciousness as most fundamental. Matter and everything else just emerges from consciousness, from this deeper level.' David Bowman, also a physicist, kind of arrived at the same conclusion. Einstein said similar things. So there's a lot of people who've thought about energy, who've thought about matter, and at the end of their lives, they're like, 'Shit, this that doesn't make. . . there's something else. There's a deeper underlying layer of reality.'
"So my perspective on this is I don't know what the truth is, but I suspect that there's kind of this underlying current and let's call it consciousness. Some people might want to call it God. Some people might want to call it, you know, energy and like dark energy or whatever. [β¦] So, there's the force or the force of consciousness, let's say, that is flowing, that's just energy. What energy does is it naturally seeks ways to transform itself or to move and to flow. This is like a fundamental property of of energy in its different forms. Energy wants to flow, wants to be transformed. So maybe there's an underlying current of consciousness.
[β¦]
"So I think it's a worthwhile hypothesis, and then it brings us to think from first principles about the nature of each of our movement, but also to see ourselves as movements, and then an energetic movement. So, we're always in flux, always changing, and there's some kind of structured or some, you know, an eddy looks like another eddy, but there's a lot of differences. The same way human beings look, you know, a lot of features we share, but we're also very different. And we have genetically identical human beings, you know, monozygotic twins that are so different and personalities and their likes and dislikes. Where does this come from? I don't know. But maybe there's a deeper layer of organization that precedes the molecular structure of our genomes and other things.
"So we can't disprove this, in the same way that we cannot prove that the materialist or the physicalist viewpoint is superior. So at this point there's been very good arguments made by Don Hoffman, who wrote this beautiful book _The Case Against Reality_, who makes the same point that matter is not most fundamental, despite what your senses are tricking you into believing. Matter is not most fundamental. There's another layer, and then you're an expression of that layer, and your own conscious experience is in a way this movement of consciousness or energy that is experiencing itself. And so this leads to really interesting questions and hypothesis which I develop in the book that I'm writing called _Energy_."
Martin Picard, PhD with Thomas P Seager, PhD @ 45:35β46:55 & 48:06β50:17 (posted 2025-09-19)
All sex hormones originate in the mitochondria. Mental health disorders as metabolic disorders. You are not a molecular machine; your brain is not broken. You are an energetic process fueled by your mitochondria
Thomas P Seager, PhD: "But what I picked up along the way is that mitochondria are the site at which all sex hormones originate. So whether it's testosterone, or even cortisol, or pregnenolone, which is a sex steroid synthesized on the inner mitochondrial membrane. If your mitochondria are not in good shape, it's no wonder you don't feel like yourself. You might lose your motivation. You might lose that zest for life that gets you up off the couch. And then when the mitochondria are restored, you can literally feel like you're a different person."
Martin Picard, PhD: "I think that's quite possible. At at this point, I would say it's a partially supported theory, right, the mitochondrial theory of mental health, or mental health disorders as metabolic disorders. I think there's a lot of strong evidence that says this is correct. If you don't feel well, right, then you don't feel like yourself, and you feel terribly depressed that you want to die. Or you have bipolar disease that you fluctuate between states of mania and states of deep depression, or you see, you hear things that other people don't hear, and you have some dissociative experiences and schizophrenia.
"All of this is not because your brain is broken. Your body is not broken. You're not a molecular machine. You are an energetic process fueled by your mitochondria. And if energy isn't flowing properly, you as a person, your energetic self changes.
"And when that happens, you know, this you might be the most first principle understanding what disease is. Right? Dis-ease, when you're not at ease, this can happen probably very quickly because your energy isn't flowing properly. And there's some example, historical example. I learned this when I was in graduate school. I was learning to study mitochondria, mitochondrial respiration, right? One major way in which mitochondria do all of these things, including making hormones, you know, the sex hormones that give the female body the ability to conceive, to carry new life, right? Progesterone, estrogen, those are made in the mitochondria. This is amazing. And testosterone determines whether you get a penis or not during embryogenesis. Testosterone is made in your mitochondria. These hormones are the basis for the survival of our species. And for some reason that nobody understands, their synthesis was converged in the same organelle, the same cellular site that's responsible for keeping the lights on and making decisions about cell life and cell death. So I think there's a profound connection there between energetics and survival of the species, and mitochondria are kind of the hub for this."
Martin Picard, PhD with Thomas P Seager, PhD @ 09:07%%11:58 (posted 2025-09-19)
Gaining insights into autism from studying melanin migration defects in Siamese cats. Blue light liberates vitamin A, which then destroys melanin sheets
Dr. Anastasia Bendebury: "Is the alpha wave signal in the thalamus different in people that have sensory defects?"
Dr. Jack Kruse: "Of course! I mean the perfect example of that is people with autism. Think about what autism functionally is: it's a neural melanin migration problem that is a transgenerational problem that happens between the mother and the father.
"And most people don't even know this, but Siamese cats [β¦] lay this out. If you go and look at all Siamese cats you'll notice they all have blue eyes. OK? And the funny thing is they have a lot of problems with their eyes, meaning sometimes they get turned in, they're all kind of crazy. The reason for that it turns out that the melanin that's in their neural tracts is really abnormal so it affects migration. [β¦]
"Melanin controls migratory patterns in neuroectoderm, and it turns out it does this through vitamin A. Vitamin A has huge effects. Well, guess what? The non-visual photoreceptor system in the brain, which melanin is part of, so is cholesterol, so is melanopsin, so is neuropsin, [β¦] in humans there it's a weak covalent bond to vitamin A. So the reason why blue light is really bad, it liberates vitamin A, and what does that do? That destroys melanin sheets anywhere they are in your body. What happens then? You get neuromigratory pattern problems. This is the reason why kids with autism actually show what I call a regressive evolution. They go back to being like a monkey who can't talk, because the melanin is not there.
"Just think about when a baby comes out of your vagina. Can the baby talk and walk and run around? The answer is no. Why? Because it's neuromelanin has not developed in its head yet. Well guess what? That system is broken in kids with autism in their sensory relays. And guess what? Are all those studies done in the ENT literature for the calyx of Held, is all that stuff done in the central retinal pathways? Yeah! It's all there! But nobody's putting it together. But guess what?
"Why have I had a Siamese cat ever since I'm 15 or 20 years old? Because I learned about melanin a long time ago. I've been fascinated by it since I'm a little boy. But I didn't know what melanin really did until I got to be about 40 years old. Then when I figured it out, I'm like, 'This is the fucking greatest story never told.'
"And when did I first tell that story, in total, of really what it means? I told it to Rick Rubin and Huberman in 10 hours, and left both of their jaws on the ground. This story is the greatest story ever told. Anybody who's interested in biology, anybody who's interested in evolution, has a duty to themselves to listen to it. This will shake your foundations.
"But I promise you this, and I swear on my life I'm right about this. You'll become a much more curious mammal after you listen to this and listen to this perspective. You will become better interviewers, because the future scientists that you're going to have on after me, you're going to say, 'Wait a minute. We need to put this through this lens. What is the effect of this on endogenous light production? How does that change the hydrogen bonding network in water? And then how does that change the paramagnetism of free radical signaling in us?' Is that fundamentally what free radicals are all about, it's about magnetic flux? Of course it is! Anything that makes an EPR signal, there's a free radical, because it has an unpaired electron. Oh shit, look at that: we're back to that goddamn physics story again.
"Look, this is a fabulous story, and I tried to tell you that I got tuned into this fabulous story through Albert Szent-GyΓΆrgyi and Becker. And I jumped down this rabbit hole and I don't want to come out of it. I want to blow up the paradigm that created me."
Dr. Jack Kruse with Dr. Anastasia Bendebury & Dr. Michael Shilo DeLay @ 02:17:18β02:21:32
The World Health Organization is a criminal organization. It needs to end. Switzerland is complicit in global acts of terrorism. Drug industry activism branded as "Public Health"
Dr. David E. Martin: "The World Health Organization is a criminal organization and we need to call it what it is. It started off in the beginning of the last century as the Opium Board. And I want you to just kind of sit with that. The Permanent Opium Board. That's what the World Health Organization was before it rebranded. Now if that sounds like a health organization, you're already delusional. What that was was the British East India Company legacy playing itself forward, and it was actually, as you know, after the Chinese disputes around the opium trade in the 1800s, where we decided to actually create a criminal cabal, not unlike OPEC, but it was for heroin and opium. Call it what it is. These are criminals.
"And it turns out that they decided to domicile in Switzerland because they actually wanted to get immunity from prosecution, and Switzerland had neutrality laws that made it most favorable. And when they wrote their charter they said they were immune from criminal behavior. So giant shock. It's a criminal organization. It's like the mob writing its own constitution going, 'Well, we're going to be the mob, we're going to write our own constitution, and you're not going to be able to investigate us regardless of what we do, because we said so.' And the rest of the world just nods their head and goes, 'Oh, OK, OK, yeah, and you said so.'
"At no point by the way is any of what I just said legal, but in in fact it is now law. Switzerland now defends the World Health Organization, and a criminal organization is running inside of Switzerland. And the Swiss are actually complicit in global acts of terrorism by virtue of shielding and harboring terrorists.
"I think we should actually start calling for Switzerland to be declared a terrorist state. Why not? We actually talk about state-sponsored terror everywhere else; why is it that we don't talk about state-sponsored terror in Switzerland? And why shouldn't we? Because they're harboring one of the largest lethal organizations on earth, the religion of that organization which leads to global terror is a religion called, allegedly, 'public health.' But 'public health' is neither public nor health. It is the advancement of drug industry activism and drug industry interests, and it is that sole purpose for which the criminal organization and the criminal cartel is established.
"So, let's start a campaign where we actually label Switzerland what it is: the state sponsor of terror which has killed more people than all of the Islamic movements, all of the craziness that's come out of other extremist programs, all of those things combined. The World Health Organization leads in fatality. So, state-sponsored terror: you got it. Switzerland, the harbor for the state-sponsored terror: absolutely. And wouldn't it be fun for us to actually see people start to hold accountability where it belongs.
"Because when it was established in 1953, remember that this was an organization that was put in place specifically to launder private sector donations into the rubric of a public, state-sanctioned version of the advancement of medical technologies. And what we have to understand is that that decision in 1953 allowed organizations like the Gates Foundation, like Gavi, like all of the UN-affiliated organizations around health, it allowed them to operate with impunity, because they can actually conduct clinical trials and kill people without any consequence. There is no standard for ___ in any of the programs that they advance as long as they can convince themselves that there is a 'world at risk.'
"Well, it turns out that if you're making the pathogens, and then you're deploying those pathogens, you can create risk wherever you want it. And the great news is because of the articulation of the history and the message of the World Health Organization, beginning ironically about a year ago, when a number of Europeans got together and invited me to do a tour of European countries where I made this presentation several times, we are succeeding in the undermining of the resolve not only of the Treaty, but I'm starting to see cracks where a number of people are starting to question whether the World Health Organization is actually a legal operation in the first place. And I want to see those cracks open up into full fissures and I want the thing to fall apart, because it has to. Because it is a criminal institution and we need to see it end."
Dr. David E. Martin with Brian Rose @ 53:46β58:23 (posted 2024-07-03)
https://rumble.com/v55af7l-dr-david-e-martin-ww3-global-catastrophe-over-2-billion-will-suffer-gruesom.html?start=3226
Human photosynthesis is driven by melanin. What melanin does
Dr. Jack Kruse: "Human photosynthesis (actually all animal photosynthesis) is driven by melanin.
[β¦]
"Hemoglobin and chlorophyll were the two main semiconductors that life used prior to the Cambrian explosion. After the Cambrian explosion, which was 650 million years ago, a third semiconductor showed up very, very quickly and kind of became the dominant player, [β¦] and the chemical is melanin.
[β¦]
"I can easily elucidate for you why melanin is important: it creates hydrogen and electrons and oxygen. That's what it fundamentally does in the cell. [β¦] A cell makes a DC electric current by charge separating water utilizing melanin to do so.
[β¦]
"The force carrier for electromagnetic force is a photon. That's light, OK? Light liberates electrons from water. OK? The same story that happens in photosynthesis, OK, except it's much more efficient when in melanin is involved. OK? In photosynthesis, only two electrons are popped out. In melanin biology, four electrons are popped out plus more hydrogen is made. So you make a bigger electric current. [β¦] The difference between hemoglobin and chlorophyll, there's 12 electrons. OK? That's the difference between simple and complex life. It turns out that melanin made more complex life even more complex because it allowed more energy production inside the cell after the Cambrian explosion. Therefore the things that we should see in life as we go further along say the history of evolution is we should see higher levels of redox chemistry. We should also see higher levels of DC electric current. We should see increased utilization of light in much more complex fashions, meaning non-linear optics should be a part of the system.
[β¦]
"The gene product that makes melanin is called POMC, proopiomelanocortin. It only gets translated or turned on by UV light. OK? So one of the peptides, the neuropeptides that's made from this besides Ξ± MSH that makes melanin, you know what it's called beta endorphin. Do you know what that means? Nature made you to be built to have a certain quantized amount of an opiate, to be outside.
[β¦]
"The mitochondria is an electromagnetic producer of light, similar to the sun, inside of every cell that actually is the composer that is directing all the boxcars in biochemistry to do this, and it works on redox signaling and light frequencies. And is that the reason why melanin controls the endogenous life story that's created inside us? Is that the reason why tryptophan, serotonin, melatonin, and leptin all have emission spectrums between 200 and 400 nanometer light that doesn't come from the sun, because maybe we make the light inside of us.
[β¦]
"What melanin is functionally doing, and why melanin is the color that it is, why certain semiconductors are the color they are, and really what melanin is functionally doing, it's actually creating a kaleidoscope inside of us that control everything in us. And when you actually look fundamentally at a cell, we have 100,000 biochemical reactions in one second. The only thing, when you just think about it, that can control that is all the different spectral frequencies that go between 200 and 1100 nanometers.
[β¦]
"It turns out that melanin and different proteins in different parts of the cell are emitting and absorbing different frequencies. So that means that, for example, the neighborhood in and around cytochrome C oxidase is loaded with infrared A light, because that's what its absorption spectrum is around. But the same thing is not true around cytochrome 2, where it's flavins and it's much more in the 400β500 range. And then it's also not true at cytochrome 1, because that's where it's in the UVA range."
Dr. Jack Kruse with Dr. Anastasia Bendebury & Dr. Michael Shilo DeLay @ 11:28β11:33, 10:25β10:54, 17:42β18:13, 19:07β20:36, 01:08:05β01:08:35, 01:26:20β01:26:58, 01:35:02β01:35:38 & 01:42:36β01:43:06
Why build a solar callus. How to build one
Dr. Jack Kruse: "I want Bill to learn how to turn on the solar callus in his body. [β¦] Solar callus, the way I like to describe it, [β¦] you go in the Louis Vuitton store with your wife. She looks at the shoes and she goes, 'Oh, baby, these hurt my feet.' And then Rick turns around and said, 'Baby, you get those shoes, wear them five times around the house, and you'll be fine.'
"You know how to break shoes in, but we don't know how to break our skin in. So when you're a white boy like me, actually all three of us, we all have skin that Fitzpatrick I or II from high latitude. What you need to know is the program's still in you. You can still make melanin, but you have to turn POMC on, [β¦] proopiomelanocortin. [β¦] That's the basis of melanin story that's there for Ξ± MSH.
"The key there is first thing you want to do to build it up, eat a lot of shellfish. Why? Because the chitin, the exoskeleton in that has a lot of chromophores that help the skin. OK?"
Rick Rubin: "Is it in anything else or only in shellfish?"
Dr. Jack Kruse: "Oh, no, it's in other things like for example, tomatoes. OK? You'll also find it in some fruits. I'm trying to think of a good one. Macadamia nuts. [β¦]"
Rick Rubin: "I like macadamia nuts as a nut."
Dr. Jack Kruse: "I do too because they have high DHA.
"The second step is then I want you to think about the circadian biology of the sun. In the morning, this red is really powerful. There's no UV. So you get a lot of red light. Red light preconditions the skin to make more UV, in other words, it helps everything in your skin, the fibroblast, the collagen, the water, it energizes it.
"And as soon as the UV comes out, the POMC that's buried in your skin turns on and you begin to make melanin.
"So melanin biology becomes upregulated because of those three things that happen. You're putting substrates in the body, which are basically proteins that allow you to assimilate light and meaning they have an absorption factor. Then you're using red light to get all the collagen ready. And then when the UVA starts, that's the stimulus to turn on Ξ± MSH.
"Then slowly, if you do this over four to six weeks, you will create your own melanin in your skin. That's the story, the idea that I got with the African-American lady with vitaligo. That's exactly what I did on her to actually stimulate it, and I wanted to know how fast it can happen. It happens quick. And then the flip side of that story is what Rick brought in part one and part two when he told us about when I go from low latitude to high latitude, I lose it pretty fast, too. [β¦]
Rick Rubin: "I have a friend who I knew back in my old life who saw me and he said, 'I didn't know you could get tan, based on how white your skin had always was. I didn't know it was possible for you to have any tans.'"
Dr. Jack Kruse: "And you know why I'm glad he just said that? Because Bill, that's the teaching case. Does a high latitude northern European, who's got Fitzpatrick type I skin, has Rick proven. . ."
Rick Rubin: "With blue eyes."
Dr. Jack Kruse: ". . .that what I just told you, with blue eyes, has Rick just proven, as the hippo and lion, he knows how to do it now? Not only that, he also is so in tune, he's like, 'Jack, when I fly home, I actually know that I lose it.' And guess what? I don't have to talk to Rick anymore. He knows. I don't have to tell him again."
Dr. Jack Kruse & Bill Gifford with Rick Rubin @ 01:56:37β02:00:36 (posted 2024-03-13)
https://youtu.be/watch?v=EHe78j9UrMI&t=6997
We're designed to eat the fish, not the pills. DHA at the sn-2 position
Max Gotzler: "I know you're also not a big fan of pills and supplements, but would you say to fish oil pills with DHA in them? Not a good idea?"
Dr. Jack Kruse: "No. And the reason I'm not a fan, it gets into the details. When it comes to quantum biology, you have to understand within the eye and the brain, DHA gets put into it in a very specific way. And it's called the sn-2 position, and I'll explain it to you very simply.
"All fats in the body have three carbons. That's the glycerol backbone. Sn-2 means the middle one. So for DHA to work optimally within the brain to have that good Ο electron cloud, it needs to be in the sn-2 position. So when you have pills that are created by man from fish, most of it is in sn-1 and sn-3. That means it's effectively useless.
"What's one of the things that food guys like you know? That polyunsaturated fats are really bad for us. They make a lot of inflammation.
"So here you think the fish oil is good, but remember the fish oil is a polyunsaturated fat. So if it's in sn-1 and sn-3, effectively that can make your highly sensitive CRP or inflammation go through the roof. No bueno.
"See the nice thing is, the way it's designed to work in nature, fish eat algae, algae do photosynthesis, and then the fish turns the DHA that's in the algae into the sn-2 position. We're designed to eat the fish, not the pills."
Dr. Jack Kruse with Max Gotzler @ 33:22β34:53 (posted 2017-02-14)
Die Flowgrade Show mit Max Gotzler: #035: Skiing In Underwear Or How To Hack Your Mitochondria With Dr. Jack Kruse
Find the Show Notes at www.flowgrade.de/jackkruse In this episode with brilliant neurosurgeon and biohacking mitochondriac, Dr. Jack Kruse, you wil...