the basis of modern virology

in medicine it is always enlightening to find natural controls. the Amish population serve as a human control --- but from a genetic standpoint, chimps serve as a control as well. chimps in captivity have an approximate 2% cancer incidence yet share 99% similar genetics as humans. either that 1% genetic difference accounts for all of the increased malignancies in humans or humans have done something to themselves that create all of the malignancies that plague our modern health. many will say that we get cancers because we live longer but captive chimpanzees live twice as long (15+ years more) than wild chimps so their lack of cancer is eye opening.

Comparative analysis of cancer genes in the human and chimpanzee genomes - PMC

Cancer is a major medical problem in modern societies. However, the incidence of this disease in non-human primates is very low. To study whether g...

People feel invigorated after an ice bath because cold receptors in your skin trigger sympathetic nervous system activation. Plasma norepinephrine and dopamine spike within seconds since your physiologic response is to "get out as fast as possible" Then your pituitary gland pumps out beta-endorphins to bind opioid receptors to counteract the pain of the cold exposure (just like a runners high) Vasoconstriction shunts blood to your core. When you exit, peripheral vasodilation creates a surge of oxygenated blood to your muscles and brain. Your cognitive override of all these systems trying to get you out of the bath is fed by a later dopamine reward and your normal warm environment then feels like a luxury.

the concept of the "6 month dental health check and cleaning" is largely a construct of dental insurance coverage. it was created as part of a pepsodent tooth paste advertisement in the 1950s and then solidified by dental insurance. when you sign up for a dental plan you are essentially prepaying for the teeth "cleaning". this is why if you are self pay they rarely ever call you to get your teeth cleaning since they know you won't want to pay for it if you haven't already prepaid via your employer plan. there has never been any scientific backing to visiting a dentist twice a year. is it a good idea...maybe but also is like visiting a mechanic when you don't have an issue...

this viral control study is the best modern one that I have read. They purposely inoculated people with H3N2 and then compared the transmission in masks vs no mask and unfortunately only one transmission event occurred. It was so hard to get people sick with H3N2 even when being quaranteened in the same room that they concluded that it must be the ventilation rather than then possibility that something might be wrong with the theory of contagion. 📄.pdf

here is my interview with Jamie Andrews, project manager for the viral control studies project. We discuss the basic methodology of viral culture research and the reason why growth medium can produce viral like particles. These viral cultures underpin all of virology as a science. His data shows that it is the starving of the cells that produce the images of viruses that we have been shown since we were little children. When a cell is dying because it is starved of nutrition, it expels its contents as it dies. The process of isolating a virus involves adding a sample from a "infected human" to a cell culture, seeing the cytopathic effects while the cell is also starved on a low nutrient medium, and then isolating the debris and sequencing it. If the debris comes from a starving cell, it puts serious doubts on the idea that the sample from an infected individual caused the cell lysis. Audio of interview: video: Viral control studies posts:

VERO Control Culture Transmission Electron Microscopy

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Full research protocol and images:

Zenodo

Vero Cell Culture Image Dataset

This dataset offers a collection of light microscope and transmission electron microscope (TEM) images of Vero E6 cell cultures , primarily aimed a...