Lite Roasters

you can add our coffee if you would like literoasters.com

comment below and zap this post and i'll send you a free half pound sample of kenyan coffee beans (US only. will dm your comment to arrange shipping via signal)

Lite Roasters 3 months ago

There is a preocupatient with experts. Every "expert" started as a non expert. You can just do things, including becoming an expert.

Lite Roasters 4 months ago

When commodity prices outpace the price inflation of the finished good, the productive economy grinds to a halt. Imaging growing coffee and needing to charge more but because the beans are so expensive no one can afford to buy the brewed cup. This is what is happening now.

Lite Roasters 4 months ago

during the first scene of the movie "Eddington" staring Joaquin Phoenix, sits the Bitcoin Standard

Lite Roasters 4 months ago

tradfi says we need more inflows to grow the asset class bitcoiners say we need less outflows to grow the asset class

Lite Roasters 4 months ago

The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet https://www.cell.com/cell/fulltext/S0092-8674(18)30520-8# >The ketogenic diet (KD) is used to treat refractory epilepsy, but the mechanisms underlying its neuroprotective effects remain unclear. Here, we show that the gut microbiota is altered by the KD and required for protection against acute electrically induced seizures and spontaneous tonic-clonic seizures in two mouse models. Mice treated with antibiotics or reared germ free are resistant to KD-mediated seizure protection. Enrichment of, and gnotobiotic co-colonization with, KD-associated Akkermansia and Parabacteroides restores seizure protection. Moreover, transplantation of the KD gut microbiota and treatment with Akkermansia and Parabacteroides each confer seizure protection to mice fed a control diet. Alterations in colonic lumenal, serum, and hippocampal metabolomic profiles correlate with seizure protection, including reductions in systemic gamma-glutamylated amino acids and elevated hippocampal GABA/glutamate levels. Bacterial cross-feeding decreases gamma-glutamyltranspeptidase activity, and inhibiting gamma-glutamylation promotes seizure protection in vivo. Overall, this study reveals that the gut microbiota modulates host metabolism and seizure susceptibility in mice.