putting 39% tarrifs on swiss gold bars is going to cause an epic gold price revaluation on trapped US supply.

Gold Market 'Upended' On Report Of US Tariffs On Swiss Bullion \ stacker news ~econ

then when gold reprices to $5k+ the US will revalue the treasury's gold holdings and use that revaluation to buy spot bitcoin in a budget neutral way.

Byzantine 4 months ago

here is a list of all the studies showing harms of linoleic acid (primary omega 6 in seed oils) Human studies 1. Ramsden CE, Zamora D, Leelarthaepin B, Majchrzak-Hong SF, Faurot KR, Suchindran CM, et al. Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis. BMJ. 2013;346:e8707. doi:10.1136/bmj.e8707 2. Ramsden CE, Zamora D, Majchrzak-Hong S, Faurot KR, Broste SK, Frantz RP, et al. Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73). JAMA Cardiol. 2016;1(3):294–302. doi:10.1001/jamacardio.2016.1313 3. Rett BS, Whelan J. Increasing dietary linoleic acid does not increase tissue arachidonic acid or inflammatory eicosanoids in healthy subjects: a randomized controlled trial. Br J Nutr. 2009;102(10):1515–25. doi:10.1017/S0007114509992980 4. Wood LG, Gibson PG, Garg ML. Circulating biomarkers are related to dietary fat intake, but not atopy or asthma, in adults. Lipids. 2004;39(11):1071–6. doi:10.1007/s11745-004-1025-3 5. Baticic L, Denham JM, Knoke JD, et al. Dietary ω-6 PUFA and systemic oxidant stress: a controlled trial. Prostaglandins Leukot Essent Fatty Acids. 2009;81(5-6):355–63. doi:10.1016/j.plefa.2009.09.004 6. Sathivasekaran S, Malathi S, Haripriyal S, Ramya K, Palanichamy R. Dietary ω-6 polyunsaturated fatty acid intake and cardiometabolic markers among Indian urban adults. Eur J Clin Nutr. 2021;75(8):1248–55. doi:10.1038/s41430-020-00789-4 7. Marklund M, Wu JHY, Imamura F, et al. Biomarkers of dietary linoleic acid and risk of incident cardiovascular disease: results from pooled cohort studies of 60 000 adults. J Intern Med. 2019;286(1):71–82. doi:10.1111/joim.12898 8. Harcombe Z, Baker JS, DiNicolantonio JJ, Grace F, Davies B. Evidence from randomised controlled trials does not support current dietary fat guidelines: a systematic review and meta-analysis. Open Heart. 2015;2(1):e000273. doi:10.1136/openhrt-2014-000273 9. Mozaffarian D, Ascherio A, Hu FB, et al. Interplay between different polyunsaturated fatty acids and risk of coronary heart disease in men. J Lipid Res. 2004;45(2):351–4. doi:10.1194/jlr.M300292-JLR200 10. Brown WVB, Knopp RH. Effects of corn oil on sudden cardiac death. Lancet. 1993;342(8876):1043–4. doi:10.1016/0140-6736(93)92433-S Animal / cell studies 11. Yang J, Nakada T, Suzuki K, et al. Dietary safflower oil supplementation increases oxidative stress markers and impairs glucose homeostasis in mice. J Nutr Sci Vitaminol. 2017;63(6):453–61. doi:10.3177/jnsv.63.453 12. Deol P, Fekete E, Woodrow J, et al. Safflower oil‐rich high‐fat diet induces obesity, inflammation, and insulin resistance in mice. PLOS ONE. 2015;10(10):e0139441. doi:10.1371/journal.pone.0139441 13. Tateyama Y, Yamamoto M, Matsumoto M. High-linoleic safflower oil induces endotoxemia and gut dysbiosis in Wistar rats. J Nutr Sci Vitaminol. 2022;68(4):304–11. doi:10.3177/jnsv.68.304 14. Nishimukai M, Yamaguchi R, Hara H, et al. Linoleic acid-enriched diet suppresses hepatic autophagy via lipid peroxidation in mice. BBA Mol Basis Dis. 2020;1866(3):165627. doi:10.1016/j.bbadis.2020.165627 15. Liu S, Li Y, Sun Y, et al. Linoleic acid induces DNA damage and suppresses insulin secretion in beta cells. Cell Rep. 2023;42(4):112315. doi:10.1016/j.celrep.2023.112315 16. Yang J, Sato H, Wang D, Wang Y. Volatile aldehydes from commercial cooking oil aerosols enhance lung-cell oxidative injury. J Agric Food Chem. 2021;69(46):13715–24. doi:10.1021/acs.jafc.1c03889 17. Halade GV, Rahman MM, Fernandez G. High-ω-6 seed oils and cardiovascular complications post-myocardial infarction in mice. J Mol Cell Cardiol. 2009;46(4):556–65. doi:10.1016/j.yjmcc.2008.12.004 18. Ramsden CE, Ringel A, Majchrzak-Hong SF, Taha AY, et al. ω-6 linoleic acid exacerbates Alzheimer’s pathology in transgenic APP/PS1 mice. J Clin Invest. 2012;122(6):2497–511. doi:10.1172/JCI58199 19. Sloop SR, Vickers KC, Kasuga D. Seed-oil formula augments septic mortality and macrophage activation neonatal piglets. Sci Rep. 2018;8(1):15723. doi:10.1038/s41598-018-34058-1 20. Thekkuttuparambil A, Sathishkumar S. High-linoleic canola diet accelerates early atherosclerotic lesions in ApoE-/- mice. J Clin Transl Endocrinol. 2024;35:100279. doi:10.1016/j.jcte.2023.100279