Artifical blood to go into clinical trial:
Japan to Begin Clinical Trials for Artificial Blood in 2025 - MedEdge MEA
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 A Japanese team is advancing artificial blood (hemoglobin here as the key component) into the clinic for testing. It's based on using "expired" normal blood so not the full package yet but considering the ever present shortage of blood-donations, if this works, this could be a start for future breakthroughs for clinical reality. Still a long way to go from here as it doesn't generate the artificial blood "from scratch" & doesn't address the other functions blood has besides the O2 transport but it's an interesting start.
Interesting cyborg-modification reported in Cell: https://www.cell.com/cell/fulltext/S0092-8674(25)00454-4 "Near-infrared spatiotemporal color vision in humans enabled by upconversion contact lenses" #science #cyborg
Giveaway 1,000 sats for the next 20 reposts, 500 for the next 15! I'm doing a Zapvertising experiment to promote my bitcoin novel „Walking Banks“ / https://www.walkingbanks.com on Nostr and test if one can broaden an audience this way . In addition to the Zapvertisment Zaps you can unlock 800000 sats: If your up for a treasure hunt, the book contains a real Bitcoin seed phrase hidden within the story. So if you can piece the right string of words together, it leads to a wallet with 800000 sats in it. No funny business, all real. The first one to figure it out gets the bitcoin. The book is out as on audiobook, e-book and print on Amazon (
Amazon.com
Amazon.com
) so go and check it out. Also, if you're using Nostr you can listen to the audiobook for free on Fountain (fountain.fm/album/JYWZOPSrol8fvWpjNt8q) or search for „Walking Banks“ in the music section. Otherwise the audiobook is also available now on Spotify, Apple Books, Google play, Kobo, and pretty much everywhere else too. #bitcoin #books #novel #story #art #zapvertising #nostr
Is ChatGTP just a human with a brain disorder? "Comparison of Large Language Model with Aphasia" paper outlining that there is "a surprising similarity between the way large language models (LLMs) like ChatGPT process information and how the brains of people with Wernicke’s aphasia function. In both cases, fluent but often incoherent output is produced, suggesting rigid internal processing patterns that can distort meaning."
Neuroscience News
AI Chatbots Mirror a Human Brain Disorder - Neuroscience News
Researchers have found a surprising similarity between the way large language models (LLMs) like ChatGPT process information and how the brains of ...
 https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202414016 #llm #ai #chatgtp #science #brain
#bitcoin image
It was dark, the moon shone bright, the green meadow was covered in snow, when a carriage sped by lightning-fast, slowly turning the corner. Inside, people were standing seated, deep in silent conversation, when a shot rabbit went ice-skating on the sandy bank. And a blond-haired young man with coal-black hair sat on a green box, which was painted red. Next to him, an old spinster, barely sixteen years old, held a butter roll in her hand, which was smeared with lard. #poetry
Good Morning and Merry Christmas ! #nostr
Another unfortunate clinical trial failure for a CNS indication (Parkinson). All primary and secondary endpoints were missed:
Findings from minzasolmin proof-of-concept ORCHESTRA study shape next steps in UCB Parkinson’s research program | UCB
Findings from minzasolmin proof-of-concept ORCHESTRA study shape next steps in UCB Parkinson’s research program | UCB
 #science #parkinson #neurodegeneration #brain
This is really interesting: https://www.nature.com/articles/s41562-024-02046-9 "Large language models surpass human experts in predicting neuroscience results" A study on how well trained LLMs can predict the "correctness" of a new neuroscience study/claim based on looking into the associations of the mentioned claims/words in the new study compared to a reference set of thousands of previously published neuroscience papers. The idea here is that there are associations hidden in the vast amount of literature out there that humans in general and singular scientists in particular just cannot read, remember, grasp and comprehend anymore due to the exponential growth in studies. Importantly all thus trained LLMs outperform a large panel of human expert in predicting whether or not a new study or a fake study is true. This is really fascinating and could have major implications to identify new disease MoA hypothesis, target validationa nd dicovery, discover hidden connections and low-hanging treatment option fruits that nobody has yet considered or simply just weed out fake or irrelevant new er publications. #ai #science #neuroscience #drugs #future #LLM #nostr
#bitcoin #nostr #memes image