Day 26 (breakthrough): AI. "Building" was once held up as a test of understanding. With AI, we can build w/out it. AlphaFold is an AI model that predicts protein structures from DNA, created w/out understanding protein folding. It changes the game. #ElusiveCures30 https://www.nature.com/articles/s41586-021-03819-2
30 days to the launch of Elusive Cures! I learned so much writing it, and I want to share it. For the next 30 days, I'll post brain & mind research breakthroughs on odd days, and highlight unmet needs on even ones. #ElusiveCures30 First breakthrough: Recording tech & why it matters. The brain is a complex system in which its parts need to be studied simultaneously b/c its emergent properties follow from their interactions. We can now do that for the first time in history. Up to 1 million neurons in mice! https://www.cell.com/neuron/abstract/S0896-6273(24)00121-1 And this is leading to ways to measure things we've never been able to before. Like how activity in the hypothalamus of a mouse gets sucked into a persistent "line attractor" to drive aggression. Understanding that is a step toward understanding emotion in humans. https://www.nature.com/articles/s41586-024-07915-x https://www.nature.com/articles/s41586-024-07915-x